Welcome

Our multi-disciplinary research team includes doctoral level personnel and students trained in biophysics and computer science. Our training and research program is part of the School of Health Information Sciences. We are also participating in various other Houston area programs such as the W. M. Keck Center for Computational and Structural Biology.

 

We have open positions for a postdoctoral researcher and graduate research assistants. Read More.

 
News

Seminar:
Structure/function of macromolecules: Eukaryotic phosphofructokinase and bacterial adhesins

(click to download flyer)

 

Prof. Teresa Ruiz, Associate Professor, Department of Molecular Physiology & Biophysics, University of Vermont, will speak about "Structure/function of macromolecules: eukaryotic
phosphofructokinase and bacterial adhesins".

Date: Wednesday, January 27, 2010
Time: 4:00PM
Place: GSBS Large Classroom (BSRB S3.8371), Mitchell Basic Sciences Research Building, 6767 Bertner, Houston, Texas 77030
For information contact: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

Seminar:
Simulations of Biomolecules in Solution and Bilayers

(click to download flyer)

 

Prof. Jeffry D. Madura, Professor & Chair, Department of Chemistry & Biochemistry, Center for Computational Sciences, Duquesne University, will speak about "Simulation of Biomolecules in Solution and Bilayers".

Date: Wednesday, January 6, 2010
Time: 4:00PM
Place: GSBS Large Classroom (BSRB S3.8371), Mitchell Basic Sciences Research Building, 6767 Bertner, Houston, Texas 77030

For information contact: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

Sculptor 1.2

A new Sculptor release, version 1.2, is available. This release includes ¨interactive global docking¨ as a major new feature, but also adds programmable-GPU accelerated rendering of atomic models, other smaller improvements and bug fixes.

 

 

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Sculptor 1.1.6

We have released version 1.1.6 of our multi-resolution molecular modeling and visualization software Sculptor. Beside various smaller improvements and bugfixes, the new release includes now routines for modeling conformational changes in low- to intermediate resolution volumetric maps. Sculptor is available for free as easy to install, ready-to-run packages for Windows, Mac OSX and Linux.

 

 

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Seminar:
GPCRs and Structure-based Drug Discovery

(click to download flyer)

 

Stefano Constanzi, Ph.D, Laboratory of Biological Modeling, National Institute of Diabetes, Digestive, and Kidney Diseases, NIH, will speak about the "the Applicability of Molecular Models of G protein-coupled receptors to Structure-based Drug Discovery".

Date: Tuesday, December 2, 2008
Time: 4:30PM
Place: GSBS Large Classroom (BSRB S3.8371), Mitchell Basic Sciences Research Building, 6767 Bertner, Houston, Texas 77030

For information contact: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

 
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Participation

Our research was / will be presented at the following conferences:

 

Invited talks:

Microscopy and Microanalysis 2010

August 1-5, Portland, OR

 

 

3D Electron Microscopy of Macromolecular Assemblies
Teresa Ruiz, Michael Radermacher, and Stefan Birmanns

 

Parallel Genetic Algorithm with Biased Initial Population for the Simultaneous Hybrid Modeling of Molecular Assemblies

Mirabela Rusu, and Stefan Birmanns

 

Poster presentation:

Biophysical Society Meeting 2010
San Francisco, California, February 20 - 24, 2010
Integrative Multi-Resolution Modeling of Pleiomorphic Biomolecular Systems
Mirabela Rusu and Stefan Birmanns

 

 

Invited talk:

4th International UVM Practical Course on Three-dimensional Cryo Electron Microscopy of Single Particles
University of Vermont, Burlington, VT, August 2 - 9, 2009
http://physioweb.med.uvm.edu/Cryo_Practical

 

 

Poster presentations:

Biophysical Society Meeting 2009
Boston, Massachusetts, February 28 - March 4, 2009
Integrative Multi-Resolution Modeling of Pleiomorphic Biomolecular Systems
Mirabela Rusu and Stefan Birmanns

Interactive Visualization of Protein Dynamics in Ribbon Mode
Manuel Wahle and Stefan Birmanns

Incorporating  Exhaustive Search and Steric Effects into Interactive Multi-Resolution Modeling
Jochen Heyd and Stefan Birmanns

Invited talk:

University of Vermont, Burlington. Hosts: Teresa Ruiz and Michael Radermacher
Sculptor: A software package for interactive and algorithmic multi-resolution modeling.
Stefan Birmanns
Burlington, VT, December 8th, 2008

Poster presentation:

18th Keck Center Annual Research Conference
Interactive Docking of Atomic Structures into 3D Cryo-Electron Microscopy Reconstructions Guided by Global Optimization,
Jochen Heyd and Stefan Birmanns
Houston, UT M. D. Anderson Cancer Center, October 3-4, 2008

Poster Award

Invited talk:

Microscopy and Microanalysis 2008
Beyond the Black-Box: Multi-Modal Hybrid Modeling of Biomolecular Assemblies
Stefan Birmanns
Albuquerque, New Mexico, August 3-7, 2008.

Poster presentation:

13th Annual Sealy Structural Biology Symposium
Interactive Docking of Atomic Structures into 3D Cryo-Electron Microscopy Reconstructions Guided by Global Optimization,
Jochen Heyd and Stefan Birmanns
Galveston, Texas, May 16-17, 2008.

Poster Session Winner

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